HEC72702
HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC50 values of 0.039 µM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers[1].
Product Specifications
CAS Number
1793063-59-8
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hec72702.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CC[C@@H]1CN(CC2=C(C(OCC)=O)[C@H](C3=CC=C(F)C=C3Br)N=C(C4=NC=CS4)N2)CCO1
Molecular Formula
C24H26BrFN4O5S
Molecular Weight
581.45
References & Citations
[1]Ren Q, et al. 3- ((R) -4- (((R) -6- (2-Bromo-4-fluorophenyl) -5- (ethoxycarbonyl) -2- (thiazol-2-yl) -3,6-dihydropyrimidin-4-yl) methyl) morpholin-2-yl) propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4. J Med Chem. 2018 Feb 8;61 (3) :1355-1374.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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