MDL 27399

MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM) . MDL 27399 can be used for research of inflammatory diseases[1].

Product Specifications

CAS Number

[131374-22-6]

UNSPSC

12352005

Target

Cathepsin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mdl-27399.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC(CCC(OC)=O)=O)C)=O)C)=O)=O)CC2=CC=CC=C2)OC

Molecular Formula

C26H36N4O8

Molecular Weight

532.59

References & Citations

[1]N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795