BMS-903452
BMS-903452 is a potent and selective GPR119 agonist for diabetes research[1].
Product Specifications
CAS Number
[1339944-47-6]
UNSPSC
12352005
Target
GPR119
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bms-903452.html
Solubility
10 mM in DMSO
Smiles
ClC1=CN=C(N2CCC(OC3=CC(N(C4=CC=C(S(=O)(C)=O)C=C4F)C=C3Cl)=O)CC2)N=C1
Molecular Formula
C21H19Cl2FN4O4S
Molecular Weight
513.37
References & Citations
[1]Wacker DA, et al. Discovery of 5-chloro-4- ((1- (5-chloropyrimidin-2-yl) piperidin-4-yl) oxy) -1- (2-fluoro-4- (methylsulfonyl) phenyl) pyridin-2 (1H) -one (BMS-903452), an antidiabetic clinical candidate targeting GPR119. J Med Chem. 2014 Sep 25;57 (18) :7499-508.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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