CGS-12066 (maleate)
CGS-12066 (maleate) is a 5-HT receptor agonist. CGS-12066 has agonist effect for 5-HT1A , 5-HT1B ,5-HT1C and 5-HT1D with pEC50 values of 6.41, 7.56, 4.05 and 7.11, respectively. CGS-12066 can be used for the research of neurological disease[1].
Product Specifications
CAS Number
[1350965-83-1]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgs-12066-maleate.html
Solubility
10 mM in DMSO
Smiles
CN1CCN(CC1)C2=NC3=C(C=CC(C(F)(F)F)=C3)N4C2=CC=C4.O=C(/C=C\C(O)=O)O
Molecular Formula
C21H21F3N4O4
Molecular Weight
450.41
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Schoeffter P, et al. Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist?. Naunyn Schmiedebergs Arch Pharmacol. 1989;339 (6) :675-683.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor
Available Sizes
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