Satratoxin H

Satratoxin H is a trichothecene with cytotoxic activity. Satratoxin H can be used for cytotoxicological studies on lymphoid cell lines[1][2].

Product Specifications

CAS Number

[53126-64-0]

UNSPSC

12352005

Hazard Statement

H301

Target

Apoptosis; p38 MAPK

Type

Natural Products

Related Pathways

Apoptosis; MAPK/ERK Pathway

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/satratoxin-h.html

Solubility

10 mM in DMSO

Smiles

CC([C@]1([H])OC(/C=C\C=C\[C@@]2([C@@H](O)C)[C@H](O)/C(CCO2)=C\C3=O)=O)([C@@]4(OC4)[C@@]([H])(C1)O5)C6(CO3)CCC(C)=C[C@]65[H]

Molecular Formula

C29H36O9

Molecular Weight

528.59

Precautions

H301

References & Citations

[1]Nielsen C, et al. Trichothecene-induced cytotoxicity on human cell lines. Mycotoxin Res. 2009 Jun;25 (2) :77-84. |[2]Eppley RM, et al. Structure of satratoxin H, a metabolite of Stachybotrys atra. Application of proton and carbon-13 nuclear magnetic resonance. J Org Chem. 1977 Jan 21;42 (2) :240-3.