Rosenonolactone

Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin and cholesterol ester transfer protein[1][2][3].

Product Specifications

CAS Number

[508-71-4]

UNSPSC

12352005

Target

CETP; Thrombin

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rosenonolactone.html

Solubility

10 mM in DMSO

Smiles

C[C@@]1([C@@]2([H])C[C@@](C=C)(C)CC1)[C@]3(O4)[C@](CC2=O)([H])[C@](C)(CCC3)C4=O

Molecular Formula

C20H28O3

Molecular Weight

316.43

References & Citations

[1]Anis I, et al. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo) . 2002;50 (4) :515-518|[2]Anis I, Ahmed S, Malik A, Yasin A, Choudary MI. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo) . 2002;50 (4) :515-518.|[3]Wang Y, Zhang L, Wang F, Li ZH, Dong ZJ, Liu JK. New Diterpenes from Cultures of the Fungus Engleromyces goetzii and Their CETP Inhibitory Activity [published online ahead of print, 2015 Apr 8]. Nat Prod Bioprospect. 2015;5 (2) :69-75.