Rosenonolactone
Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin and cholesterol ester transfer protein[1][2][3].
Product Specifications
CAS Number
508-71-4
UNSPSC
12352005
Target
CETP; Thrombin
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rosenonolactone.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1([C@@]2([H])C[C@@](C=C)(C)CC1)[C@]3(O4)[C@](CC2=O)([H])[C@](C)(CCC3)C4=O
Molecular Formula
C20H28O3
Molecular Weight
316.43
References & Citations
[1]Anis I, et al. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo) . 2002;50 (4) :515-518|[2]Anis I, Ahmed S, Malik A, Yasin A, Choudary MI. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo) . 2002;50 (4) :515-518.|[3]Wang Y, Zhang L, Wang F, Li ZH, Dong ZJ, Liu JK. New Diterpenes from Cultures of the Fungus Engleromyces goetzii and Their CETP Inhibitory Activity [published online ahead of print, 2015 Apr 8]. Nat Prod Bioprospect. 2015;5 (2) :69-75.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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