BRD0418

BRD0418 is a diversity-oriented synthesis (DOS) molecule that regulates the expression of tribbles pseudokinase 1. BRD0418 has the effect of causing hot lipoprotein metabolism from fat production to clearance. BRD0418 can be used in the study of coronary artery disease (CAD) [1].

Product Specifications

CAS Number

1565827-99-7

UNSPSC

12352005

Target

CaMK

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/brd0418.html

Purity

99.22

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C[C@@H]1C[C@@]2([C@@]([H])(OC3=CC=C(C=C23)N(C)C)[C@@H](O1)CO)[H])NCC4=CC=C(C=C4)OC5=CC=CC=C5

Molecular Formula

C29H32N2O5

Molecular Weight

488.57

References & Citations

[1]Nagiec MM, et al. Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression. PLoS One. 2015 Mar 26;10 (3) :e0120295.