Fengabine

Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression[1].

Product Specifications

CAS Number

[80018-06-0]

Product Name Alternative

SL 79229

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fengabine.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(C=C1/C(C2=CC=CC=C2Cl)=N\CCCC)Cl

Molecular Formula

C17H17Cl2NO

Molecular Weight

322.23

References & Citations

[1]Ascalone V, et al. Determination of the GABAergic antidepressant drug fengabine and some of its metabolites in plasma by capillary gas chromatography with electron-capture detection. J Chromatogr. 1989;490 (1) :81-90.|[2] Lloyd KG, et al. Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. J Pharmacol Exp Ther. 1987;241 (1) :245-250.