SKF1
Product Specifications
UNSPSC Description
SKF1 is a FK506 suppressor, causes a mitochondrially induced death in low salt, concomitant with the release of reactive oxygen species (ROS)[1].
Target Antigen
FKBP; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/skf1.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1CCCCC1)C2=CC=C(C(NCCCCCCCC)=N)C=C2.[H]Cl
Molecular Weight
409.01
References & Citations
[1]Rebecca A Butcher, et al. A small molecule suppressor of FK506 that targets the mitochondria and modulates ionic balance in Saccharomyces cerevisiae. Chem Biol. 2003 Jun;10(6):521-31.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123454/SKF1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123454/
Clinical Information
No Development Reported
CAS Number
678997-25-6
Curated Selection
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