KM-233
KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research[1].
Product Specifications
CAS Number
628263-22-9
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/km-233.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C(C2=CC=CC=C2)(C)C)=CC3=C1[C@]4([H])CC(C)=CC[C@]4(C(C)(O3)C)[H]
Molecular Formula
C25H30O2
Molecular Weight
362.50
References & Citations
[1]Duntsch C, et al. Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. J Neurooncol. 2006 Apr;77 (2) :143-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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