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Ro 19-1400

Ro 19-1400 is a platelet-activating factor antagonist that directly inhibits immunoglobulin E-dependent mediator release[1].

Product Specifications

CAS Number

122937-55-7

UNSPSC

12352005

Target

Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ro-19-1400.html

Solubility

10 mM in DMSO

Smiles

O=C(CCC[N+]1=CSC=C1)OC[C@H](COC(NCCCCCCCCCCCCCCCCCC)=O)OC(OC)=O.[OH-]

Molecular Formula

C31H56N2O8S

Molecular Weight

616.85

References & Citations

[1]M. Pretolani, et al. Limited interference of specific Paf antagonists with hyper-responsiveness to Paf itself of lungs from actively sensitized guinea-pigs.Br J Pharmacol. 1989 Jun; 97 (2) : 433–442.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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