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Fotagliptin

Fotagliptin is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM) . Fotagliptin displays great security in rat and dog. Fotagliptin can be used for Type 2 diabetes mellitus research[1].

Product Specifications

CAS Number

[1312954-58-7]

Product Name Alternative

SAL067 (free base)

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fotagliptin.html

Purity

99.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=O)=NN=C(N2C[C@@H](CCC2)N)N1CC3=C(C=CC(F)=C3)C#N

Molecular Formula

C17H19FN6O

Molecular Weight

342.37

References & Citations

[1]Wang Z, et al. Development and validation of a UPLC-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine. Bioanalysis. 2017 Feb;9 (4) :381-393.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

DPP-4

Available Sizes

Curated Selection

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