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Zolertine (hydrochloride)

Zolertine hydrochloride is an α-adrenoceptor antagonist with a pKi of 6.81 in rat liver (α1B-adrenoceptors) and 6.35 in rabbit liver (α1A-adrenoceptors) membranes[1].

Product Specifications

CAS Number

7241-94-3

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/zolertine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

[H]Cl.N1(CCN(CC1)CCC2=NN=NN2)C3=CC=CC=C3

Molecular Formula

C13H19ClN6

Molecular Weight

294.78

References & Citations

[1]Ibarra M, et al. The alpha-adrenoceptor antagonist, zolertine, inhibits alpha1D- and alpha1A-adrenoceptor-mediated vasoconstriction in vitro. J Auton Pharmacol. 2000 Jun;20 (3) :139-45.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α adrenergic receptor

Frequently Asked Questions

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