11β-HSD1-IN-12

11β-HSD1-IN-12 is a 11β-HSD1 inhibitor (Example 21 in reference patent) . 11β-HSD1 regenerates active glucocorticoids from inactive forms and is important in regulating intracellular glucocorticoid concentration. 11β-HSD1-IN-12 can be used in the research of obesity and metabolic syndrome[1].

Product Specifications

CAS Number

[872506-67-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

11β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/11β-hsd1-in-12.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1CN(S(=O)(C2=CC=CC(Cl)=C2C)=O)CCC1)NC3CCCCC3

Molecular Formula

C19H27ClN2O3S

Molecular Weight

398.95

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Wenqing Yao, et al. N-substituted piperidines and their use as pharrmaceuticals. Patent. US20060004049A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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