11β-HSD1-IN-12
11β-HSD1-IN-12 is a 11β-HSD1 inhibitor (Example 21 in reference patent) . 11β-HSD1 regenerates active glucocorticoids from inactive forms and is important in regulating intracellular glucocorticoid concentration. 11β-HSD1-IN-12 can be used in the research of obesity and metabolic syndrome[1].
Product Specifications
CAS Number
[872506-67-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/11β-hsd1-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CN(S(=O)(C2=CC=CC(Cl)=C2C)=O)CCC1)NC3CCCCC3
Molecular Formula
C19H27ClN2O3S
Molecular Weight
398.95
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Wenqing Yao, et al. N-substituted piperidines and their use as pharrmaceuticals. Patent. US20060004049A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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