EAD1
Product Specifications
UNSPSC Description
EAD1 is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 also induces apoptosis[1].
Target Antigen
Apoptosis; Autophagy
Type
Reference compound
Related Pathways
Apoptosis;Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ead1.html
Solubility
10 mM in DMSO
Smiles
CN(CCNCC1=CN(CC2=CC=C(Cl)C=C2)N=N1)CCNC3=CC=NC4=CC(Cl)=CC=C34
Molecular Weight
484.42
References & Citations
[1]Lars Ulrik Nordstrøm, et al. Discovery of Autophagy Inhibitors With Antiproliferative Activity in Lung and Pancreatic Cancer Cells. ACS Med Chem Lett. 2015 Jan 8;6(2):134-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123056/EAD1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123056/
Clinical Information
No Development Reported
CAS Number
1644388-26-0
Curated Selection
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