EAD1
EAD1 is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 also induces apoptosis[1].
Product Specifications
CAS Number
[1644388-26-0]
UNSPSC
12352005
Target
Apoptosis; Autophagy
Type
Reference compound
Related Pathways
Apoptosis; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ead1.html
Solubility
10 mM in DMSO
Smiles
CN(CCNCC1=CN(CC2=CC=C(Cl)C=C2)N=N1)CCNC3=CC=NC4=CC(Cl)=CC=C34
Molecular Formula
C24H27Cl2N7
Molecular Weight
484.42
References & Citations
[1]Lars Ulrik Nordstrøm, et al. Discovery of Autophagy Inhibitors With Antiproliferative Activity in Lung and Pancreatic Cancer Cells. ACS Med Chem Lett. 2015 Jan 8;6 (2) :134-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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