Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Nicotinamide riboside

Nicotinamide riboside, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2].

Product Specifications

CAS Number

1341-23-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Sirtuin

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/nicotinamide-riboside.html

Purity

99.99

Solubility

10 mM in DMSO

Smiles

NC(C1=C[N+]([C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)=CC=C1)=O

Molecular Formula

C11H15N2O5

Molecular Weight

255.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Cantó C, et al. The NAD (+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15 (6) :838-47.|[2]Bing Gong, et al. Nicotinamide Riboside Restores Cognition Through an Upregulation of Proliferator-Activated Receptor-γ Coactivator 1α Regulated β-Secretase 1 Degradation and Mitochondrial Gene Expression in Alzheimer's Mouse Models. Neurobiol Aging. 2013 Jun;34 (6) :1581-8.|[3]Collin D Heer, et al. Coronavirus and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity. bioRxiv. 2020 Apr 30;2020.04.17.047480.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite; SIRT1; SIRT3

Citation 01

ACS Appl Mater Interfaces. 2024 May 1;16 (17) :21383-21399.|ACS Appl Mater Interfaces. 2025 Aug 20;17 (33) :47497-47511.|Br J Pharmacol. 2025 Apr 13.|Cell Biosci. 2021 Nov 10;11 (1) :192.|Cells. 2023 Oct 2;12 (19) :2396.|Commun Biol. 2023 Mar 2;6 (1) :235.|FASEB J. 2022 Jul;36 (7) :e22418.|FASEB J. 2024 Apr 15;38 (7) :e23600.|Mol Ther. 2023 Jan 4;31 (1) :193-210.|Redox Biol. 2022 Nov:57:102507.|Res Sq. 2025 Mar 31.|Basic Res Cardiol. 2024 Jun;119 (3) :403-418.|Bone Res. 2025 Jan 26;13 (1) :18.|Curr Issues Mol Biol. 2024 Feb 1;46 (2) :1291-1307.|Exp Eye Res. 2024 Nov:248:110126.|Int J Biol Macromol. 2025 Jul 5;320 (Pt 1) :145750.|Invest Ophthalmol Vis Sci. 2024 Jul 1;65 (8) :1.|J Ginseng Res. 2025 May 10.|Nat Commun. 2023 Jan 16;14 (1) :240.|Toxicol Appl Pharmacol. 2024 Aug 9:117066.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

LIPH (NM_139248) Human Over-expression Lysate
LY403385 100 µg

LIPH (NM_139248) Human Over-expression Lysate

Sign In for Pricing
View Details
RHBDF2 Rabbit Polyclonal Antibody
TA360845 100 µL

RHBDF2 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Phospho-EGFR (Y1045) Recombinant Rabbit Monoclonal Antibody [PSH03-28]
HA721970 100 µL

Phospho-EGFR (Y1045) Recombinant Rabbit Monoclonal Antibody [PSH03-28]

Sign In for Pricing
View Details
PHF1 Human Gene Knockout Kit (CRISPR)
KN402906 1 Kit

PHF1 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
S100A4 (Marker of Tumor Metastasis) (S100A4/1482), CF647 conjugate, 0.1mg/mL
BNC471482-500 1x 500 µL

S100A4 (Marker of Tumor Metastasis) (S100A4/1482), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
HA Tag (16.43), CF740 conjugate, 0.1mg/mL
BNC742543-500 1x 500 µL

HA Tag (16.43), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details