Tomopenem

Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL) . Antianaerobic activity[1].

Product Specifications

CAS Number

[222400-20-6]

Product Name Alternative

CS-023; RO4908463; R-115685

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tomopenem.html

Solubility

10 mM in DMSO

Smiles

OC(C1=C(S[C@H]2C[C@H](N(C2)C)C(N3C[C@H](CC3)NC(CNC(N)=N)=O)=O)[C@H](C)[C@@]([C@@]4([H])[C@H](O)C)([H])N1C4=O)=O

Molecular Formula

C23H35N7O6S

Molecular Weight

537.63

References & Citations

[1]Kaori Tanaka, et al. In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. Antimicrob Agents Chemother. 2009 Jan;53 (1) :319-22.