Tomopenem
Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL) . Antianaerobic activity[1].
Product Specifications
CAS Number
222400-20-6
Product Name Alternative
CS-023; RO4908463; R-115685
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tomopenem.html
Solubility
10 mM in DMSO
Smiles
OC(C1=C(S[C@H]2C[C@H](N(C2)C)C(N3C[C@H](CC3)NC(CNC(N)=N)=O)=O)[C@H](C)[C@@]([C@@]4([H])[C@H](O)C)([H])N1C4=O)=O
Molecular Formula
C23H35N7O6S
Molecular Weight
537.63
References & Citations
[1]Kaori Tanaka, et al. In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. Antimicrob Agents Chemother. 2009 Jan;53 (1) :319-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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