Kihadanin B
Kihadanin B is a citrus limonoid that can be purified from the peels of immature Citrus unshiu. Kihadanin B suppresses adipogenesis through repression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes[1].
Product Specifications
CAS Number
73793-68-7
UNSPSC
12352005
Target
Akt; PPAR
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kihadanin-b.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@]34[C@@H](C(O[C@@H](C5=CC(O)OC5=O)[C@@]4(CC[C@]1([H])[C@@]6([C@@](C(C)(OC(C=C6)=O)C)([H])CC2=O)C)C)=O)O3
Molecular Formula
C26H30O9
Molecular Weight
486.51
References & Citations
[1]Baba S, et al. A Limonoid Kihadanin B from Immature Citrus unshiu Peels Suppresses Adipogenesis through Repression of the Akt-FOXO1-PPARγ Axis in Adipocytes. J Agric Food Chem. 2016 Dec 28;64 (51) :9607-9615.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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