Pterisolic acid B

Pterisolic acid B (Compound 2) is an ent-Kaurane diterpenoid. Pterisolic acid B can be isolated from fern Pteris semipinnata (Pteridaceae) [1].

Product Specifications

CAS Number

[1401419-86-0]

UNSPSC

12352211

Target

Keap1-Nrf2

Type

Natural Products

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pterisolic-acid-b.html

Solubility

10 mM in DMSO

Smiles

O=C1C([C@@]2([H])C[C@]13C([C@]4([C@]([C@@](C)(CCC4)C(O)=O)([H])[C@@H](O)C3)C)=CC2)=C

Molecular Formula

C20H26O4

Molecular Weight

330.42

References & Citations

[1]Ting Dong, et al. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Sci Rep. 2016 Jan 13:6:19231.|[2]Wang F, et al. Pterisolic acids A-F, new ent-kaurane diterpenoids from the fern Pteris semipinnata. Chem Pharm Bull (Tokyo) . 2011;59 (4) :484-7.