Pterisolic acid B
Product Specifications
UNSPSC Description
Pterisolic acid B (Compound 2) is an ent-Kaurane diterpenoid. Pterisolic acid B can be isolated from fern Pteris semipinnata (Pteridaceae)[1].
Target Antigen
Keap1-Nrf2
Type
Natural Products
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pterisolic-acid-b.html
Solubility
10 mM in DMSO
Smiles
O=C1C([C@@]2([H])C[C@]13C([C@]4([C@]([C@@](C)(CCC4)C(O)=O)([H])[C@@H](O)C3)C)=CC2)=C
Molecular Weight
330.42
References & Citations
[1]Ting Dong, et al. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Sci Rep. 2016 Jan 13:6:19231.|[2]Wang F, et al. Pterisolic acids A-F, new ent-kaurane diterpenoids from the fern Pteris semipinnata. Chem Pharm Bull (Tokyo). 2011;59(4):484-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122946/Pterisolic-acid-B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122946/
Clinical Information
No Development Reported
CAS Number
1401419-86-0
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