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Arg-Gly-Asp-Ser (TFA)

Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1[1].

Product Specifications

Product Name Alternative

RGDS peptide (TFA) ; Fibronectin tetrapeptide (TFA)

UNSPSC

12352209

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/arg-gly-asp-ser-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CO)C(O)=O)[C@H](CC(O)=O)NC(CNC([C@@H](N)CCCNC(N)=N)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C17H28F3N7O10

Molecular Weight

547.44

References & Citations

[1]Aguzzi MS, et al. Intracellular targets of RGDS peptide in melanoma cells. Mol Cancer. 2010 Apr 22;9:84.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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