Arg-Gly-Asp-Ser (TFA)
Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1[1].
Product Specifications
Product Name Alternative
RGDS peptide (TFA) ; Fibronectin tetrapeptide (TFA)
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arg-gly-asp-ser-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CO)C(O)=O)[C@H](CC(O)=O)NC(CNC([C@@H](N)CCCNC(N)=N)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C17H28F3N7O10
Molecular Weight
547.44
References & Citations
[1]Aguzzi MS, et al. Intracellular targets of RGDS peptide in melanoma cells. Mol Cancer. 2010 Apr 22;9:84.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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