HS-131
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers[1].
Product Specifications
CAS Number
2084850-40-6
UNSPSC
12171500
Target
HSP
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hs-131.html
Solubility
10 mM in DMSO
Smiles
CC1=NN(C2=CC(NCCCOCCOCCOCCOCCOCCCNCC3=CC=C(C=C3)C(/C=C/C4=[N+](C5=CC=CC=C5C4(C)C)CCCCS(=O)([O-])=O)=C\C=C6N(C7=CC=CC=C7C\6(C)C)CCCCS(=O)(O)=O)=C(C=C2)C(N)=O)C8=C1C(CC(C)(C8)C)=O
Molecular Formula
C71H95N7O13S2
Molecular Weight
1318.68
References & Citations
[1]Takuya Osada, et al. In Vivo Detection of HSP90 Identifies Breast Cancers with Aggressive Behavior. Clin Cancer Res. 2017 Dec 15;23 (24) :7531-7542.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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