BCL6 PROTAC 1
BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) PROTAC. BCL6 PROTAC 1 inhibits BCL6 cell reporter with an IC50 value of 8.8 µM. BCL6 PROTAC 1 significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines. BCL6 PROTAC 1 can be used in tumor related research[1].
Product Specifications
CAS Number
[2257479-54-0]
UNSPSC
12352005
Target
BCL6; PROTACs
Type
Reference compound
Related Pathways
Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl6-protac-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N1)C(N2C(C(C(OCCOCCOCCCNC(CCC(N3CCN(C4=NC=C(Cl)C(N5)=N4)[C@@H](COCCOC6=CC5=CC(CC7)=C6N(C)C7=O)C3)=O)=O)=CC=C8)=C8C2=O)=O)CCC1=O
Molecular Formula
C45H52ClN9O12
Molecular Weight
946.40
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122829/BCL6-PROTAC-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122829/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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