Mcl1-IN-5
Mcl1-IN-5 (compound 21) is a MCL-1 inhibitor. Mcl1-IN-5 can be used for the research of cancers[1].
Product Specifications
CAS Number
2056238-04-9
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcl1-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2)C3=CC=CC=C3CC[C@]1([H])NC(C[C@H](NCCCN(C)C(C[C@H](CC4=CC(CCC5=CC=CC=C5)=C(Cl)C=C4)NC2=O)=O)CC6=CC=C(S(C)(=O)=O)C=C6)=O
Molecular Formula
C45H52ClN5O6S
Molecular Weight
826.44
References & Citations
[1]Johannes JW, et al. Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors [published correction appears in ACS Med Chem Lett. 2017 Oct 18;8 (11) :1204]. ACS Med Chem Lett. 2016;8 (2) :239-244.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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MAPK3 (Mitogen-activated Protein Kinase 3, MAPK 3, MAP Kinase 3, ERT2, Extracellular Signal-regulated Kinase 1, ERK1, ERK-1, Insulin-stimulated MAP2 Kinase, MAP Kinase Isoform p44, Microtubule-associated Protein 2 Kinase, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, P44ERK1, p44-ERK1, P44MAPK, p44-MAPK, PRKM3, MGC20180) (Biotin)
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