Mcl1-IN-5
Product Specifications
UNSPSC Description
Mcl1-IN-5 (compound 21) is a MCL-1 inhibitor. Mcl1-IN-5 can be used for the research of cancers[1].
Target Antigen
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcl1-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2)C3=CC=CC=C3CC[C@]1([H])NC(C[C@H](NCCCN(C)C(C[C@H](CC4=CC(CCC5=CC=CC=C5)=C(Cl)C=C4)NC2=O)=O)CC6=CC=C(S(C)(=O)=O)C=C6)=O
Molecular Weight
826.44
References & Citations
[1]Johannes JW, et al. Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors [published correction appears in ACS Med Chem Lett. 2017 Oct 18;8(11):1204]. ACS Med Chem Lett. 2016;8(2):239-244.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122721/Mcl1-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122721/
Clinical Information
No Development Reported
CAS Number
2056238-04-9
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