SK-216
SK-216 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that acts as an anti-metastatic agent for human osteosarcoma and inhibits lung metastasis of human osteosarcoma[1].
Product Specifications
CAS Number
[654080-03-2]
UNSPSC
12352005
Target
PAI-1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sk-216.html
Purity
99.43
Solubility
H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O[Na])C(CCCCCOC1=CC=C2C=C(C3=NC4=CC(C(C)(C)C)=CC=C4O3)C=CC2=C1)C(O[Na])=O
Molecular Formula
C29H29NNa2O6
Molecular Weight
533.52
References & Citations
[1]Minori Tsuge, et al. SK-216, a Novel Inhibitor of Plasminogen Activator Inhibitor-1, Suppresses Lung Metastasis of Human Osteosarcoma. Int J Mol Sci. 2018 Mar 5;19 (3) :736.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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