PPACK II
PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].
Product Specifications
CAS Number
74392-49-7
UNSPSC
12352005
Target
Kallikrein
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ppack-ii.html
Solubility
10 mM in DMSO
Smiles
N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O
Molecular Formula
C25H33ClN6O3
Molecular Weight
501.02
References & Citations
[1]Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106 (4) :440-5.|[2]Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340 (1-2) :163-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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