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PPACK II

PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].

Product Specifications

CAS Number

74392-49-7

UNSPSC

12352005

Target

Kallikrein

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ppack-ii.html

Solubility

10 mM in DMSO

Smiles

N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O

Molecular Formula

C25H33ClN6O3

Molecular Weight

501.02

References & Citations

[1]Kentaro Takayama, et al. Identification of a degrading enzyme in human serum that hydrolyzes a C-terminal core sequence of neuromedin U. Biopolymers. 2016 Nov 4;106 (4) :440-5.|[2]Alexander Belenky, et al. The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma. Clin Chim Acta. 2004 Feb;340 (1-2) :163-72.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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