Almurtide
Almurtide (nor-MDP), a muramyl dipeptide derivative with anti-inflammatory and anti-tumor activity. Almurtide also shows protective effects against intraperitoneal Pseudomonas aeruginosa infection or intravenously Candida albicans infection in mice. Almurtide also inhibits the carcinogenic Friend leukemia virus[1][2][3].
Product Specifications
CAS Number
61136-12-7
UNSPSC
12352211
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/almurtide.html
Solubility
10 mM in DMSO
Smiles
CC(N[C@@H](C=O)[C@H]([C@H](O)[C@H](O)CO)OCC(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O)=O
Molecular Formula
C18H30N4O11
Molecular Weight
478.45
References & Citations
[1]Díaz-Eufracio BI, et al. Exploring the chemical space of peptides for drug discovery: a focus on linear and cyclic penta-peptides. Mol Divers. 2018 May;22 (2) :259-267. |[2]Fraser-Smith E B, et al. Protective effect of muramyl dipeptide analogs against infections of Pseudomonas aeruginosa or Candida albicans in mice. Infection and immunity, 1981, 34 (3) : 676-683. |[3]Acevedo H F, et al. Prevention of oncogenic viral infections in mice with CGP 11637, a synthetic muramyl dipeptide analog[J]. Antimicrobial agents and chemotherapy, 1985, 28 (5) : 589-596.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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