Thrazarine
Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].
Product Specifications
CAS Number
[120128-14-5]
Product Name Alternative
FR 900840
UNSPSC
12352211
Target
Antibiotic
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thrazarine.html
Solubility
10 mM in DMSO
Smiles
N[C@H](C(O)=O)COC(C([C@@H](C)O)=[N+]=[N-])=O
Molecular Formula
C7H11N3O5
Molecular Weight
217.18
References & Citations
[1]Kameyama T, et al. Thrazarine, a new antitumor antibiotic. I. Taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo) . 1988 Nov;41 (11) :1561-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
