1'-Hydroxy bufuralol-d9
1'-Hydroxy bufuralol-d9 is a deuterium labeled 1'-Hydroxy bufuralol. 1'-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity[1][2].
Product Specifications
CAS Number
1185069-74-2
UNSPSC
12352005
Target
Cytochrome P450; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.9
Solubility
10 mM in DMSO
Smiles
CC(C1=C2C(C=C(O2)C(O)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=CC=C1)O
Molecular Formula
C16H14D9NO3
Molecular Weight
286.41
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.|[2]Evangelos P Daskalopoulos, et al. D₂-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D. Mol Pharmacol. 2012 Oct;82 (4) :668-78.|[3]H Yamazaki, et al. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46 (3) :568-77.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx532644 96 Tests
Mouse Mediator of RNA polymerase II transcription subunit 25 (MED25) ELISA Kit
Sign In for Pricing
View Details 
MBS452154-01 48 Tests
Human A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit
Sign In for Pricing
View Details MBS452154-02 96 Tests
Human A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit
Sign In for Pricing
View Details MBS452154-03 5x 96 Tests
Human A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit
Sign In for Pricing
View Details MBS452154-04 10x 96 Tests
Human A Disintegrin And Metalloproteinase With Thrombospondin 5 (ADAMTS5) ELISA Kit
Sign In for Pricing
View Details