[Orn8]-Urotensin II (human)

[Orn8]-Urotensin II (human), a peptide analog of urotensin II, is a UT receptor agonist. [Orn8]-Urotensin II (human) increases intracellular calcium levels in HEK293[1].

Product Specifications

CAS Number

[479065-85-5]

UNSPSC

12352209

Target

Urotensin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/orn8-urotensin-ii-human.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCN)=O)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)C(C)C)=O)NC([C@H](CC(O)=O)NC([C@H]3N(CCC3)C([C@H]([C@H](O)C)NC([C@@H](N)CCC(O)=O)=O)=O)=O)=O)=O)CC4=CC=CC=C4)N[C@H]1CC5=CNC6=CC=CC=C56

Molecular Formula

C63H83N13O18S2

Molecular Weight

1374.54

References & Citations

[1]Camarda V, et al. Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors. Eur J Pharmacol. 2004 Sep 13;498 (1-3) :83-6.|[2]Camarda V, et al. A new ligand for the urotensin II receptor. Br J Pharmacol. 2002 Oct;137 (3) :311-4.