JNJ-40255293
JNJ-40255293 is a high-affinity human A 2A receptor antagonist with a KiKi of 7.5 nM. JNJ-40255293 can be used in the research of neurodegenerative diseases such as Parkinson's disease[1].
Product Specifications
CAS Number
[1147271-25-7]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jnj-40255293.html
Purity
98.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C=C(C=C2)OCCN3CCOCC3)C4=NC(N)=NC(C5=CC=CC=C5)=C41
Molecular Formula
C23H22N4O3
Molecular Weight
402.45
References & Citations
[1]John R Atack, et al. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease. ACS Chem Neurosci. 2014 Oct 15;5 (10) :1005-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15145026 1 Vial
Lentiviral mouse Cstf3 shRNA (UAS) - Lentiviral mouse Cstf3 shRNA (UAS) (100)
Ask
View Details 
MBS6334719-01 0.2 mL
PLCL2, CT (PLCL2, KIAA1092, PLCE2, Inactive phospholipase C-like protein 2, Phospholipase C-epsilon-2) (APC)
Ask
View Details MBS6334719-02 5x 0.2 mL
PLCL2, CT (PLCL2, KIAA1092, PLCE2, Inactive phospholipase C-like protein 2, Phospholipase C-epsilon-2) (APC)
Ask
View Details 