Necrostatin-1 (inactive control)
Necrostatin-1 (Nec-1) (inactive control) is an inactive analog of Necrostatin-1 (HY-15760) . Necrostatin-1 is a potent necroptosis inhibitor[1].
Product Specifications
CAS Number
[64419-92-7]
Product Name Alternative
Nec-1 (inactive control)
UNSPSC
12352005
Target
Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/necrostatin-1-inactive-control.html
Purity
99.9
Solubility
DMF : 20 mg/mL (ultrasonic; warming) |DMSO : 14 mg/mL (ultrasonic; warming)
Smiles
O=C(N1)C(CC2=CNC3=CC=CC=C32)NC1=S
Molecular Formula
C12H11N3OS
Molecular Weight
245.30
References & Citations
[1]Degterev A, et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol. 2008 May;4 (5) :313-21.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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