TX-1123
TX-1123 is a potent protein tyrosine kinase (PTK) inhibitor for Src, eEF2-K, and PKA, and EGFR-K/PKC. TX-1123 is a cyclo-oxygenase (COX) inhibitor with IC50 values of 1.16 μM and 15.7 μM for COX2 and COX1, respectively. TX-1123 has low mitochondrial toxicity. TX-1123 can be used in research of cancer[1][2].
Product Specifications
CAS Number
157397-06-3
UNSPSC
12352005
Target
CaMK; COX; EGFR; PKA; PKC; Src
Type
Reference compound
Related Pathways
Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; Neuronal Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tx-1123.html
Solubility
10 mM in DMSO
Smiles
O=C1/C(C(C=C1)=O)=C\C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Molecular Formula
C20H24O3
Molecular Weight
312.40
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
Frequently Asked Questions
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