ML138
ML138, a κ opioid receptor agonist, is a MLPCN probe[1].
Product Specifications
CAS Number
[1355243-24-1]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ml138.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(CSC2=NN=C(C3=NC=CC=C3)N2CC4=CC=CO4)C=C1Cl
Molecular Formula
C19H14Cl2N4OS
Molecular Weight
417.31
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kevin J Frankowski, et al. Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. ACS Chem Neurosci. 2012 Mar 21;3 (3) :221-236.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
κ Opioid Receptor/KOR
Curated Selection
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