Pravastatin lactone
Pravastatin lactone is a potent HMG-CoA inhibitor. Pravastatin Lactone is a metabolite of pravastatin. Pravastatin lactone reduces blood cholesterol levels by inhibiting cholesterol synthesis[1].
Product Specifications
CAS Number
[85956-22-5]
UNSPSC
12352005
Hazard Statement
H302
Target
HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pravastatin-lactone.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC[C@H](C)C(O[C@@H]1[C@@]2([H])C(C=C[C@@H]([C@@H]2CC[C@@H]3C[C@H](CC(O3)=O)O)C)=C[C@H](C1)O)=O
Molecular Formula
C23H34O6
Molecular Weight
406.51
Precautions
H302
References & Citations
[1]Corsini A, et, al. Pharmacology of competitive inhibitors of HMG-CoA reductase. Pharmacol Res. 1995 Jan;31 (1) :9-27.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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