Melitracen
Melitracen (Melitracene) is an orally active tricyclic antidepressant and it is also a bipolar thymoleptic with activating properties. Melitracen inhibits 3H-5-HT and 14H-5-HT with IC50s of 670 nM and 5500 nM, respectively. Melitracen can be used for the research of depression and anxiety[1][2].
Product Specifications
CAS Number
5118-29-6
Product Name Alternative
Melitracene; N 7001; Trausabun
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/melitracen.html
Solubility
10 mM in DMSO
Smiles
CN(CC/C=C1C2=C(C(C)(C3=CC=CC=C\13)C)C=CC=C2)C
Molecular Formula
C21H25N
Molecular Weight
291.43
References & Citations
[1]Shimamoto K, et al. Relationship between the restriction of food intake and Melitracen, an antidepressant, in the rat. Acta Sch Med Univ Kioto. 1967 Jul;40 (1) :25-37.|[2]Hyttel J. Effect of a specific 5-HT uptake inhibitor, citalopram (Lu 10-171), on 3H-5-HT uptake in rat brain synaptosomes in vitro. Psychopharmacology (Berl) . 1978 Dec 15;60 (1) :13-8. doi: 10.1007/BF00429172. PMID: 104340.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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