4-Aminopteroylaspartic acid

4-Aminopteroylaspartic acid (Amino-An-Fol) inhibits the growth of psittacosis virus (6BC) in tissue cultures at concentrations which were not toxic. 4-Aminopteroylaspartic acid inhibts growth of meningopneumonitis virus in embryonated eggs or tissue culture[1].

Product Specifications

CAS Number

[25312-31-6]

Product Name Alternative

Amino-An-Fol

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/4-aminopteroylaspartic-acid.html

Solubility

10 mM in DMSO

Smiles

NC1=NC(N)=NC2=C1N=C(CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CC(O)=O)=O)C=N2

Molecular Formula

C18H18N8O5

Molecular Weight

426.39

References & Citations

[1]MORGAN HR. Factors related to the growth of psittacosis virus (strain 6BC) . I. Pteroylglutamic acid, vitamin B12, and citrovorum factor. J Exp Med. 1952;95 (3) :269-276.