AQ4
AQ4 is a topoisomerase II inhibitor and DNA intercalator as a chemically stable cytotoxic agent in many human tumor lines[1].
Product Specifications
CAS Number
[70476-63-0]
UNSPSC
12352005
Hazard Statement
H302, H410
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aq4.html
Purity
97.34
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(C(C3=C(C=CC(NCCN(C)C)=C13)NCCN(C)C)=O)C(O)=CC=C2O
Molecular Formula
C22H28N4O4
Molecular Weight
412.48
Precautions
H302, H410
References & Citations
[1]Luan X, et al. A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia. Adv Sci (Weinh) . 2018 May 28;5 (8) :1800034.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15395250 1 Vial
Lentiviral human TRAK1 sgRNA gene knockout kit - Lentiviral human TRAK1 sgRNA gene knockout kit (25)
Ask
View Details 
