SaRI 59-801

SaRI 59-801 is an orally effective hypoglycemic compound with stimulation activity of insulin secretion. SaRI 59-801 decreases blood glucose in several species and to elevate plasma insulin in rats and mice[1][2].

Product Specifications

CAS Number

[80565-58-8]

UNSPSC

12352005

Hazard Statement

H301-H315-H319-H335

Target

Insulin Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sari-59-801.html

Solubility

10 mM in DMSO

Smiles

OC(C1=C(NC2=C1C=CC=C2)C3=C(ON=C3CC)C)CN(C)C

Molecular Formula

C18H23N3O2

Molecular Weight

313.39

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hanson RL, et al. Stimulation of insulin secretion from isolated rat islets by SaRI 59-801. Diabetes. 1985;34 (6) :548-552.|[2]Hanson RL, et al. Stimulation of insulin secretion from isolated rat islets by SaRI 59-801. Diabetes. 1985 Jun;34 (6) :548-52.