JP104
JP104, a aryl carbamate, is an irreversible FAAH inhibitor with a pIC50 of ~8[1].
Product Specifications
CAS Number
887264-45-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jp104.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC(C2=CC=CC(C(N)=O)=C2)=CC=C1)NCCCCCCCCCC#C
Molecular Formula
C25H30N2O3
Molecular Weight
406.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Catherine Michaux, et al. Binding mode of new (thio) hydantoin inhibitors of fatty acid amide hydrolase: comparison with two original compounds, OL-92 and JP104. Bioorg Med Chem Lett. 2006 Sep 15;16 (18) :4772-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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