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JP104

JP104, a aryl carbamate, is an irreversible FAAH inhibitor with a pIC50 of ~8[1].

Product Specifications

CAS Number

[887264-45-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/jp104.html

Solubility

10 mM in DMSO

Smiles

O=C(OC1=CC(C2=CC=CC(C(N)=O)=C2)=CC=C1)NCCCCCCCCCC#C

Molecular Formula

C25H30N2O3

Molecular Weight

406.52

Precautions

H302, H315, H319, H335

References & Citations

[1]Catherine Michaux, et al. Binding mode of new (thio) hydantoin inhibitors of fatty acid amide hydrolase: comparison with two original compounds, OL-92 and JP104. Bioorg Med Chem Lett. 2006 Sep 15;16 (18) :4772-6.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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