ALLO-1
Product Specifications
UNSPSC Description
ALLO-1, an autophagy receptor, is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif[1].
Target Antigen
Atg8/LC3; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/allo-1.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C(N(C1C)CC2=CC=CC=C2)=O)C3=CC=C(C=C3)Cl
Molecular Weight
314.77
References & Citations
[1]Sato M, et al. The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans. Nat Cell Biol. 2018 Jan;20(1):81-91.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121546/ALLO-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121546/
Clinical Information
No Development Reported
CAS Number
37468-32-9
Curated Selection
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