ALLO-1
ALLO-1, an autophagy receptor, is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif[1].
Product Specifications
CAS Number
37468-32-9
UNSPSC
12352005
Hazard Statement
H302-H317-H319-H400
Target
Atg8/LC3; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/allo-1.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C(N(C1C)CC2=CC=CC=C2)=O)C3=CC=C(C=C3)Cl
Molecular Formula
C17H15ClN2O2
Molecular Weight
314.77
Precautions
P261-P264-P270-P272-P273-P280-P302+P352-P305+P351+P338-P330-P362+P364-P391-P501
References & Citations
[1]Sato M, et al. The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans. Nat Cell Biol. 2018 Jan;20 (1) :81-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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