IWP-2-V2

IWP-2-V2 is a IWP-2 (HY-13912) analogue that retains activity against the Wnt/β-catenin pathway[1].

Product Specifications

CAS Number

[877618-79-6]

UNSPSC

12352005

Target

Wnt

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/iwp-2-v2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NC2=C(S1)C=C(C=C2)C)CSC(N3CC4=CC=CC=C4)=NC5=C(C3=O)SCC5

Molecular Formula

C23H20N4O2S3

Molecular Weight

480.63

References & Citations

[1]Chen B, et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol. 2009 Feb;5 (2) :100-7. doi: 10.1038/nchembio.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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