Docosahexaenoyl glycine

Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs channels and restore the function of IKs channels with LQT1 mutation[1].

Product Specifications

CAS Number

[132850-40-9]

UNSPSC

12352209

Target

Endogenous Metabolite; Potassium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/docosahexaenoyl-glycine.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CNC(CC/C=C/C/C=C/C/C=C/C/C=C/C/C=C/C/C=C/CC)=O

Molecular Formula

C24H35NO3

Molecular Weight

385.54

References & Citations

[1]Mark A Skarsfeldt, et al. Polyunsaturated fatty acid-derived IKs channel activators shorten the QT interval ex-vivo and in-vivo. Acta Physiol (Oxf) . 2020 Aug;229 (4) :e13471.