URB754
URB754 is a potent inhibitor of the endocannabinoid-deactivating enzyme monoacylglycerol lipase (MGL) with an IC50 of 200 nM[1].
Product Specifications
CAS Number
[86672-58-4]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/urb754.html
Purity
97.77
Solubility
10 mM in DMSO
Smiles
O=C1OC(NC2=CC=C(C)C=C2)=NC3=CC=C(C)C=C13
Molecular Formula
C16H14N2O2
Molecular Weight
266.29
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Tarzia G, et al. Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) . Ann Chim. 2007;97 (9) :887-894.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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