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Acotiamide-d6

Acotiamide-d6 is a deuterium labeled Acotiamide. Acotiamide is an orally active and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia[1][2].

Product Specifications

CAS Number

[2749427-97-0]

Product Name Alternative

Z-338-d6 (free base) ; YM443-d6 (free base)

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

O=C(C1=CSC(NC(C2=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C2O)=O)=N1)NCCN(C(C)C)C(C)C

Molecular Formula

C21H24D6N4O5S

Molecular Weight

456.59

References & Citations

[1]Nowlan ML, et al. Acotiamide: first global approval. Drugs. 2013 Aug;73 (12) :1377-83.|[2]Attia KAM, et al. Spectrofluorimetric determination of acotiamide hydrochloride trihydrate in the presence of its oxidative degradation product. Luminescence. 2018 Jun;33 (4) :806-811.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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