Spiraprilat
Spiraprilat is a potent angiotensin-converting enzyme (ACE) inhibitor. Spiraprilat has ability to improve left ventricular (LV) function and metabolism in anesthetized open-chest dogs with acute ventricular failure (ALVF) [1].
Product Specifications
CAS Number
83602-05-5
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/spiraprilat.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@@H]1CC2(SCCS2)CN1C([C@H](C)N[C@@H](CCC3=CC=CC=C3)C(O)=O)=O
Molecular Formula
C20H26N2O5S2
Molecular Weight
438.56
References & Citations
[1]Nakazawa M, et al. Effects of spiraprilat, an angiotensin-converting enzyme inhibitor, on anesthetized dogs in a new model of acute left ventricular failure. J Cardiovasc Pharmacol. 1993 Oct;22 (4) :585-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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