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(Z) -Lafutidine

(Z) -Lafutidine ((Z) -FRG-8813) is a potent histamine H2 receptor antagonist. (Z) -Lafutidine shows anti-secretory and gastroprotective activities[1].

Product Specifications

CAS Number

206449-93-6

Product Name Alternative

(Z) -FRG-8813

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/z-lafutidine.html

Solubility

10 mM in DMSO

Smiles

O=C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O

Molecular Formula

C22H29N3O4S

Molecular Weight

431.55

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hirakawa N, et al. A novel histamine 2 (H2) receptor antagonist with gastroprotective activity. II. Synthesis and pharmacological evaluation of 2-furfuryl-thio and 2-furfurylsulfinyl acetamide derivatives with heteroaromatic rings. Chem Pharm Bull (Tokyo) . 1998;46 (4) :616-622.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

H2 Receptor

Available Sizes

Frequently Asked Questions

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