(Z) -Lafutidine
(Z) -Lafutidine ((Z) -FRG-8813) is a potent histamine H2 receptor antagonist. (Z) -Lafutidine shows anti-secretory and gastroprotective activities[1].
Product Specifications
CAS Number
206449-93-6
Product Name Alternative
(Z) -FRG-8813
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/z-lafutidine.html
Solubility
10 mM in DMSO
Smiles
O=C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O
Molecular Formula
C22H29N3O4S
Molecular Weight
431.55
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Hirakawa N, et al. A novel histamine 2 (H2) receptor antagonist with gastroprotective activity. II. Synthesis and pharmacological evaluation of 2-furfuryl-thio and 2-furfurylsulfinyl acetamide derivatives with heteroaromatic rings. Chem Pharm Bull (Tokyo) . 1998;46 (4) :616-622.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H2 Receptor
Available Sizes
Frequently Asked Questions
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